The 2025 ISC High Performance conference, taking place in Hamburg, Germany from June 10 to 13, stands poised to become a landmark gathering in the rapidly evolving realms of high-performance computing (HPC), artificial intelligence (AI), and quantum technologies. As one of the premier international platforms, ISC 2025 brings together a diverse community of scientists, engineers, and industry leaders with a shared mission: to explore the latest breakthroughs and foster collaboration across academia, government, and private sectors. The event’s comprehensive agenda underscores the accelerating pace of innovation in computing technologies and their critical role in tackling some of today’s most complex scientific and industrial challenges.
At the heart of the conference lie several standout features that reflect the vibrancy and forward momentum of these fields. One highlight is the Nimbus Innovation Awards – SuperComputing Edition 2025, an accolade dedicated to recognizing groundbreaking projects and visionary innovators pushing the boundaries of HPC and quantum computing. These awards showcase a remarkable evolution in scientific computing, particularly as quantum computing begins to complement traditional supercomputers by addressing problems that classical methods struggle to solve efficiently. Presentations from the award winners offer attendees insights into cutting-edge methodologies applied across life sciences, materials science, and beyond, illustrating how hybrid computational approaches are reshaping research possibilities.
The structure of ISC 2025 caters thoughtfully to the varied interests and expertise of its attendees, spanning a mix of conference sessions, exhibitions, tutorials, workshops, and special events scheduled over four action-packed days. The agenda combines invited talks and contributed sessions designed to delve deep into technical innovations and practical applications. For example, tutorials and workshops scheduled for June 13 provide opportunities for participants to acquire hands-on experience with emerging computational techniques. Additionally, the conference’s exhibitions and vendor programs serve as a showcase for industry leaders unveiling the latest advancements in GPU cloud computing, HPC networking, machine learning, and quantum hardware and software. These technologies are not only transforming research workflows but also driving new industry standards, demonstrating the interconnectedness of academic research and commercial innovation.
Quantum computing emerges as a central theme at ISC 2025, highlighting its transformative potential to revolutionize how we solve computational problems. Unlike classical supercomputers, quantum computers can tackle specific classes of problems considered intractable, such as complex optimization tasks, molecular simulations, and cryptographic challenges. The conference features dedicated sessions and exhibitions illustrating quantum applications across diverse sectors, from accelerating drug discovery to optimizing logistics and advancing materials design. ISC 2025’s focus coincides with the International Year of Quantum Science and Technology (IYQ 2025), marking a century since the inception of quantum mechanics. This commemoration amplifies the conference’s role as a global platform for showcasing strides in quantum research and fostering collaborations that cross disciplinary boundaries, inspiring new partnerships between physicists, computer scientists, engineers, and industry innovators.
Beyond the technical innovations on display, ISC 2025 places strong emphasis on leadership and community development as pillars of sustained progress. The appointment of Vince Arnold as president of the Chartered Institution of Building Services Engineers (CIBSE) for the 2025-2026 term exemplifies the importance of visionary leadership in navigating the challenges and opportunities of rapidly advancing technology landscapes. Concurrently, initiatives like the Student Cluster Competition, held from June 10 to 12, engage emerging HPC talents in real-world problem-solving exercises, nurturing hands-on skills and promoting a spirit of collaboration among the next generation of supercomputing experts. These efforts underscore ISC’s commitment to not just showcasing technology, but also cultivating an inclusive and forward-looking community.
The conference’s innovative spirit extends beyond the physical venue through the hybrid Innovation Showcase, an online platform offering bite-sized presentations from 14 organizations. This approach broadens accessibility, welcoming participation from those unable to travel to Hamburg and enabling a global audience to engage with cutting-edge research and industrial applications. The event’s open call for contributions from academia, government laboratories, and industry enriches its diversity and dynamism, facilitating a comprehensive exploration of current HPC and quantum advancements through research papers, posters, tutorials, and workshops. This wide-ranging engagement strengthens ISC’s role as a catalyst for scientific discourse and technology diffusion.
Industry partnerships, notably with technology leaders like NVIDIA, further highlight the convergence of HPC, AI, and quantum computing at ISC 2025. NVIDIA’s presence emphasizes breakthroughs in energy-efficient computing and AI inferencing that complement HPC capabilities, collectively addressing some of the biggest challenges in climate modeling, personalized medicine, and data-driven scientific discovery. These collaborations illustrate a trend toward integrated solutions that leverage the strengths of multiple computational paradigms, pushing the envelope of what is achievable in both research and practical applications.
The impact of ISC’s advancing technologies often transcends the lab and server room, touching unexpected domains such as veterinary medicine. Anecdotes like the successful intensive dental surgery on rescued Armenian bears suffering from toothaches illustrate how computational methods and materials science innovations have real-world implications for animal welfare and healthcare. This humanizing dimension reminds us that high-level computational breakthroughs celebrated at ISC conferences frequently translate into tangible benefits, improving lives across diverse contexts.
In essence, the ISC High Performance 2025 conference is far more than a technology showcase—it is a vibrant hub of innovation, education, and leadership within the computing sciences. By honoring cutting-edge achievements through the Nimbus Innovation Awards, facilitating deep learning via tutorials and workshops, and spotlighting quantum computing’s groundbreaking potential, ISC 2025 exemplifies a dynamic ecosystem driving scientific and industrial advancement worldwide. Its inclusive programming, forward-thinking agenda, and commitment to fostering cross-sector collaboration collectively position the conference as a central forum for shaping the future of HPC, AI, and quantum technologies and their application to global challenges.
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